Tantalum Cluster Derivatization Kit

Tantalum Bromide Clusters are used for the preparation of heavy-atom derivatives for structure determination of biological macromolecules by X-ray analysis.

This electron-rich compound can be employed in single and multiple isomorphous replacement (SIR and MIR) experiments in order to induce measurable changes of the diffraction intensities required for phase calculation.

The cluster also contains two strong anomalous scatterers suitable for multiple anomalous diffraction (MAD) experiments.

Tantalum bromide clusters have been successfully employed in several structural studies because of their high electron-density, solubility in aqueous solutions and stability over a wide pH range.

Each kit contains 6 – 1 mg solid aliquots of hexatantalum tetradecabromide.