NanoSoft Cryo Tweezers
Cryo-Tweezers work with all generations of the FEI Vitrobot and offer multiple features that make the sample preparation process more dependable and effortless for the user.
The cryo tweezers now come with a metal clamp. The logo on the clamp may be slightly different than the image. We are working on updating our images.
Tweezers for plunge-freezing cryo-TEM sample preparation systems have remained the same across all platforms and generations. Fighting to get the tweezer dovetail on and off of the plunger – and fighting with a plastic “O-ring” to grasp and release the delicate TEM grid.
Experienced sample preparation experts will find a smoother process. Early experiences for beginners will become less stressful, leading to fewer lost grids and more successful imaging as they prepare their first samples.
The Cryo-Tweezers are fully assembled, including the modified reverse action tweezers and clamp, made for use with the FEI/Thermo Fisher Vitrobot.
See Video and Learn More DetailsProduct Information
The video is showing the old version of the cryo tweezers. The old version has the plastic clamp. When ordering you will receive the new version of the cryo tweezers which use the metal clamp.
the FEI Vitrobot plunger with a dovetail geometry. The tight mate of the dovetail makes it difficult to attach and detach the tweezers, and is sometimes difficult to control, leading to crashing the sample grid into the ethane cup walls. Our Plunge-Clamp is spring loaded and when opened is easy to attach to and remove from the plunger. When closed in the natural state it forms a tight mate to the plunger. The clamp self-centers to align the tweezers axis with the axis of the plunger rod to ensure that it plunges safely through to the liquid ethane.
so an "O-ring" is utilized to keep the tweezers closed on the sample grid. This requires you to carefully slide 
the O-ring up and down the tweezers, while holding the tips closed, whenever you want to grab or release the grid. Our reverse action tweezers hold the grid securely in their natural state and require just a small pinch to release the grid into the grid box. Commercially available reverse-action tweezers are too wide for the Vitrobot blotting arms - our modified version fits easily between the blotting pads without interfering with the blot.